The spokes on a standard spoked wheel hold it in tension. If the spokes lose tension, they start to break and the rim will buckle. A Loopwheel is not held in tension by its springs.
For me, base on this design, as long as you can maintain the hub to be: ground to hub distance would always be greater than the hub to the horizontal distance (radius) to the rim. then you should be fine.

Loopwheels use an off-the-shelf bicycle wheel but removes the spokes in place of a spring system between the hub and the rim for integral suspension. That suspension is made up of three carbon composite springs that act as shock absorbers with 45mm of travel, cushioning the rider for a smooth and comfortable ride. Unlike standard bike suspension systems, it provides tangential suspension, allowing your ride to absorb shocks from all directions — even from the front and rear.
Repairs aren't the only pricey setback, When it comes time to replace a high-performance, low-profile tire, the cost can be staggering. Take, for example, the 2011 Chrysler 300C AWD. By the time 35,000 miles pass, according to TireRack.com, you'll be looking at an $1,128 bill if you opt for the factory Michelin Pilot HX MXM4 tires in 235/55R19 size, not including mount, balance, tire disposal, or the four-wheel alignment that's always a good idea before investing in new rubber.